This site is intended for U.S. healthcare professionals.

Visit Pfizer Medical

Menu

Close

Sign InLog OutTherapy AreasProductsOrder VaccinesOrder SamplesOrderMaterialsCo-pay Cards & Patient Savings OffersRequest SamplesHospital ProductsVaccinesPatient AssistancePfizer Oncology TogetherPfizer RxPathwaysPfizer Dermatology Patient AccessExplore ContentEventsMaterialsVideosContact
Search

Menu

Close

HomePrevnar 20®Prevnar 20®Serotypes matterAdministrationBurden of diseaseBurden
of diseasePneumococcal pneumoniaLinked Mega MenuBurden
of diseaseLinkLinkLinkLinkLabelLinkLinkLinkLinkLabelLinkLinkLinkLinkIPDPatient profilesPatient
profilesAge 50+DiabetesAsthmaCOPDChronic heart diseaseRisk for all underlying medical conditionsClinical studiesClinical studiesBuilt on PCV13CAPiTAStudy 1 designStudy 1 resultsStudy 1 safetyStudy 6 designStudy 6 resultsStudy 6 safetyCDC recommendationsAccess & supportAccess & supportMedicareCommercial health plansMaterialsVideos
Prescribing InformationIndicationPatient SiteOrder Prevnar 20®
Pneumococcal pneumonia can have a serious impact on your patients1,2
of pneumococcal disease cases in US adults aged >50 were due to nonbacteremic pneumococcal pneumonia in 2019.1
of pneumococcal disease cases in US adults aged >50 were due to nonbacteremic pneumococcal pneumonia in 2019.1
~500,000nonbacteremic pneumococcal pneumonia infections estimated in the US in 20191~225,000pneumococcal pneumonia hospitalizations estimated in the US annually2*~1 in 4adults will die within 1 year following pneumococcal pneumonia hospitalization2*
Prevnar 20® helps protect against 20 serotypes that can cause pneumococcal pneumonia.3,4
Prevnar 20® helps protect against 20 serotypes that can cause pneumococcal pneumonia.3,4
View patient types eligible for Prevnar 20Patient profilesLoadingUAD=urinary antigen detection.
*Based on a population-based study examining 5402 adults hospitalized for community-acquired pneumonia over a 2-year period from 2014 to 2016 in Louisville, Kentucky. One of the study limitations includes reliance on the UAD-24 platform for serotyping that can detect 24 of ~100 Streptococcus pneumoniae serotypes (1, 2, 3, 4, 5, 6A, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F, and 33F), potentially underestimating S. pneumoniae cases and serotype distribution and the prepandemic time frame which may not reflect current epidemiology.2,5References:Thomas RE. Pneumococcal pneumonia and invasive pneumococcal disease in those 65 and older: rates of detection, risk factors, vaccine effectiveness, hospitalisation and mortality. Geriatrics (Basel). 2021;6(1):13.Ramirez J, Furmanek S, Chandler TR, et al; The University of Louisville Pneumonia Study Group. Epidemiology of pneumococcal pneumonia in Louisville, Kentucky, and its estimated burden of disease in the United States. Microorganisms. 2023;11(11):2813.Prevnar 20® (Pneumococcal 20-valent Conjugate Vaccine) Prescribing Information. Wyeth Pharmaceuticals LLC, 2023. Kobayashi M, Leidner AJ, Gierke R, et al. Expanded recommendations for use of pneumococcal conjugate vaccines among adults aged ≥50 years: recommendations of the Advisory Committee on Immunization Practices — United States, 2024. MMWR Morb Mortal Wkly Rep. 2025;74(1):1-8.Ramirez JA, Hubler RA, Ali M, et al. Streptococcus pneumoniae serotype distribution among US adults hospitalized with community-acquired pneumonia, 2019-2020. Open Forum Infect Dis. 2024;12(1):ofae727.Burden of disease Order Prevnar 20 for your office by registering for Prime Get started Loading
This site is intended only for U.S. healthcare professionals. The products discussed in this site may have different product labeling in different countries. The information provided is for educational purposes only.Manufactured by Wyeth Pharmaceuticals LLC.
Marketed by Pfizer Inc.
PP-PNR-USA-3105 © 2025 Pfizer Inc.
All rights reserved. September 2025

To report an adverse event, please call 1-800-438-1985

Pfizer for Professionals 1-800-505-4426

This site is intended only for U.S. healthcare professionals. The products discussed in this site may have different product labeling in different countries. The information provided is for educational purposes only.

© 2025 Pfizer Inc. All rights reserved.

PP-PNR-USA-3105
You are now leaving PfizerPro You are now leaving a Pfizer operated website. Links to all outside sites are provided as a resource to our visitors. Pfizer accepts no responsibility for the content of sites that are not owned and operated by Pfizer.PP-MCL-USA-0367
INDICATION AND SELECT SAFETY INFORMATION
  • Prevnar 20® is a vaccine approved for:​​​​​
    • active immunization for the prevention of invasive disease caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F in individuals 6 weeks of age and older
    • active immunization for the prevention of pneumonia caused by S. pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F in individuals 18 years of age and older
  • The indication for the prevention of pneumonia caused by S. pneumoniae serotypes 8, 10A, 11A, 12F, 15B, 22F, and 33F in individuals 18 years of age and older is approved under accelerated approval based on immune responses as measured by opsonophagocytic activity (OPA) assay. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial
SELECT SAFETY INFORMATION
  • Do not administer Prevnar 20® to individuals with severe allergic reaction (eg, anaphylaxis) to any component of Prevnar 20® or to diphtheria toxoid
  • Safety and immunogenicity data on Prevnar 20® are not available for individuals in immunocompromised groups and vaccination should be considered on an individual basis. Based on experience with pneumococcal vaccines, individuals with altered immunocompetence may have reduced immune responses to Prevnar 20®
IMPORTANT SAFETY INFORMATION
  • Do not administer Prevnar 20® to individuals with severe allergic reaction (eg, anaphylaxis) to any component of Prevnar 20® or to diphtheria toxoid
  • Safety and immunogenicity data on Prevnar 20® are not available for individuals in immunocompromised groups and vaccination should be considered on an individual basis. Based on experience with pneumococcal vaccines, individuals with altered immunocompetence may have reduced immune responses to Prevnar 20®
  • In individuals 18 years of age and older, the most commonly reported solicited adverse reactions (>10%) were pain at the injection site, muscle pain, fatigue, headache, and arthralgia. Additionally, injection site swelling was also reported (>10%) in individuals 18 through 59 years of age
Patients should always ask their healthcare providers for medical advice about adverse events. You are encouraged to report negative side effects of vaccines to the US Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC). Visit http://www.vaers.hhs.gov or call 1-800-822-7967.

Please click for Prevnar 20® Full Prescribing Information.INDICATION
  • Prevnar 20® is a vaccine approved for:
    • active immunization for the prevention of invasive disease caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F in individuals 6 weeks of age and older
    • active immunization for the prevention of pneumonia caused by S. pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F in individuals 18 years of age and older
  • The indication for the prevention of pneumonia caused by S. pneumoniae serotypes 8, 10A, 11A, 12F, 15B, 22F, and 33F in individuals 18 years of age and older is approved under accelerated approval based on immune responses as measured by opsonophagocytic activity (OPA) assay. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial