This site is intended for U.S. healthcare professionals.

Visit Pfizer Medical

Menu

Close

Sign InLog Out ProductsOrderMaterialsCo-pay Cards & Patient Savings OffersRequest SamplesHospital ProductsVaccinesPatient AssistancePfizer Oncology TogetherPfizer RxPathwaysPfizer Dermatology Patient AccessExplore ContentEventsMaterialsVideosContact
Search

Menu

Close

HomePrevnar 20®Prevnar 20® Serotypes matterBurden of diseaseIPDCAPPatient profilesPatient
profilesAge 50+: Arlene, Age 51Diabetes: David, Age 46Asthma: Carly, Age 30COPD: William, Age 48Age 65+: Tyrell, Age 67 Risk for All Underlying Medical ConditionsMary, 65: Healthy ≥65; Unknown Vaccination HistoryCDC recommendationsClinical studiesClinical studiesBuilt on PCV13CAPiTAStudy 1 designStudy 1 resultsStudy 1 safetyStudy 6 designStudy 6 resultsStudy 6 safetyAdministrationAccess & supportAccess & supportMedicareCommercial health plansMaterialsVideosEvents
Prescribing InformationIndicationsPatient SiteOrder Prevnar 20®
Age 50+Arlene, age 51AGE 50+ puts adult patients at greater risk1[2.7x] greater risk for pneumococcal pneumonia compared with healthy adults aged 18 to 49.3,4

Over half of IPD cases in adults aged 50 to 64 years from 2018 to 2022 were attributed to the serotypes included in Prevnar 20.5

IPD hospitalization in adults aged 50 to 64 is similar in cost to adults aged 65 to 75 (~$10,500) and results in a 7.6% in-hospital mortality rate.6†

The CDC recommends Prevnar 20 for eligible adult patients aged 50 and older who are vaccine-naïve or whose vaccination history is unknown.7‡

References*Vs healthy adults in the same age range.1,2

2.7x greater risk for pneumococcal pneumonia compared with healthy adults aged 18 to 49.2,3

Over half of IPD cases in adults aged 50 to 64 years from 2018 to 2022 were attributed to the serotypes included in Prevnar 20®.4

IPD hospitalization in adults aged 50 to 64 is similar in cost to adults aged 65 to 75 (~$10,500) and results in a 7.6% in-hospital mortality rate.5*

The CDC recommends Prevnar 20 for eligible adult patients aged 50 and older who are vaccine-naïve or whose vaccination history is unknown.6†

Prevnar 20® completes the CDC recommendation in one dose for ALL eligible adult patients.6,7 Vaccinate today.

Prevnar 20® completes the CDC recommendation in one dose for ALL eligible adult patients.6,7 Vaccinate today.

View risk data for pneumococcal pneumonia View risk chart LoadingReferencesCDC=Centers for Disease Control and Prevention; COPD=chronic obstructive pulmonary disease; IPD=invasive pneumococcal disease; PCV7=7-valent pneumococcal conjugate vaccine.*[New footnote TK.]2†Data from a retrospective analysis of 90 US hospitals in the BD Insights Research Database. Administrative data and orders for antimicrobial agents were analyzed for hospitalized adult patients (aged ≥18 years) admitted between October 2015 and February 2020.6‡Also applies to people who received PCV7 at any age and have received no other pneumococcal vaccines.7References:Kobayashi M. Summary of Work Group interpretation of EtR and policy options: PCV use in adults aged ≥50 years. Presented at: Advisory Committee on Immunization Practices; October 23, 2024; Atlanta, GA. Accessed October 23, 2024. https://www.cdc.gov/acip/downloads/slides-2024-10-23-24/04-Kobayashi-Pneumococcal-508.pdf[Reference TK.]Grant LR, Meche A, McGrath L, et al. Risk of pneumococcal disease in US adults by age and risk profile. Open Forum Infect Dis. 2023;10(5):ofad192. Grant LR, Meche A, McGrath L, et al. Risk of pneumococcal disease in US adults by age and risk profile supplementary data. Open Forum Infect Dis. 2023;10(5):S1-S35. Kobayashi M. Summary of Work Group interpretations of EtR and policy option on PCV21 use in adults. Presented at: Advisory Committee on Immunization Practices; June 27, 2024; Atlanta, GA. Accessed September 23, 2024. https://www.cdc.gov/acip/downloads/slides-2024-06-26-28/04-Pneumococcal-Kobayashi-508.pdfMohanty S, Cossrow N, Yu KC, Ye G, White M, Gupta V. Clinical and economic burden of invasive pneumococcal disease and noninvasive all-cause pneumonia in hospitalized US adults: a multicenter analysis from 2015 to 2020. Int J Infect Dis. 2024;143:107023.Centers for Disease Control and Prevention. Pneumococcal vaccine timing for adults. October 2024. Accessed November 13, 2024. https://www.cdc.gov/pneumococcal/downloads/Vaccine-Timing-Adults-JobAid.pdfPrevnar 20® (Pneumococcal 20-valent Conjugate Vaccine) Prescribing Information. Wyeth Pharmaceuticals LLC, 2023.Patient ProfilesDownload CDC recommendations for 50+ Download LoadingOrder Prevnar 20 for your office by registering for Prime Get started LoadingReferencesCDC=Centers for Disease Control and Prevention; COPD=chronic obstructive pulmonary disease; IPD=invasive pneumococcal disease; PCV7=7-valent pneumococcal conjugate vaccine.*Data from a retrospective analysis of 90 US hospitals in the BD Insights Research Database. Administrative data and orders for antimicrobial agents were analyzed for hospitalized adult patients (aged ≥18 years) admitted between October 2015 and February 2020.5†Also applies to people who received PCV7 at any age and have received no other pneumococcal vaccines.6References:Kobayashi M. Summary of Work Group interpretation of EtR and policy options: PCV use in adults aged ≥50 years. Presented at: Advisory Committee on Immunization Practices; October 23, 2024; Atlanta, GA. Accessed October 23, 2024. https://www.cdc.gov/acip/downloads/slides-2024-10-23-24/04-Kobayashi-Pneumococcal-508.pdfGrant LR, Meche A, McGrath L, et al. Risk of pneumococcal disease in US adults by age and risk profile. Open Forum Infect Dis. 2023;10(5):ofad192. Grant LR, Meche A, McGrath L, et al. Risk of pneumococcal disease in US adults by age and risk profile supplementary data. Open Forum Infect Dis. 2023;10(5):S1-S35. Kobayashi M. Summary of Work Group interpretations of EtR and policy option on PCV21 use in adults. Presented at: Advisory Committee on Immunization Practices; June 27, 2024; Atlanta, GA. Accessed September 23, 2024. https://www.cdc.gov/acip/downloads/slides-2024-06-26-28/04-Pneumococcal-Kobayashi-508.pdfMohanty S, Cossrow N, Yu KC, Ye G, White M, Gupta V. Clinical and economic burden of invasive pneumococcal disease and noninvasive all-cause pneumonia in hospitalized US adults: a multicenter analysis from 2015 to 2020. Int J Infect Dis. 2024;143:107023.Centers for Disease Control and Prevention. Pneumococcal vaccine timing for adults. October 2024. Accessed November 13, 2024. https://www.cdc.gov/pneumococcal/downloads/Vaccine-Timing-Adults-JobAid.pdfPrevnar 20® (Pneumococcal 20-valent Conjugate Vaccine) Prescribing Information. Wyeth Pharmaceuticals LLC, 2023.
This site is intended only for U.S. healthcare professionals. The products discussed in this site may have different product labeling in different countries. The information provided is for educational purposes only.
Manufactured by Wyeth Pharmaceuticals LLC.

Marketed by Pfizer Inc.

PP-PNR-USA-2559 © 2025 Pfizer Inc.
All rights reserved. January 2025

To report an adverse event, please call 1-800-438-1985

Pfizer for Professionals 1-800-505-4426

This site is intended only for U.S. healthcare professionals. The products discussed in this site may have different product labeling in different countries. The information provided is for educational purposes only.

© 2025 Pfizer Inc. All rights reserved.

PP-PNR-USA-2559
You are now leaving PfizerPro You are now leaving a Pfizer operated website. Links to all outside sites are provided as a resource to our visitors. Pfizer accepts no responsibility for the content of sites that are not owned and operated by Pfizer.PP-MCL-USA-0367
INDICATIONS AND SELECT SAFETY INFORMATION
  • Prevnar 20® is indicated for active immunization for the prevention of invasive disease caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F in individuals 6 weeks of age and older
  • Prevnar 20® is indicated for active immunization for the prevention of pneumonia caused by S. pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F in individuals 18 years of age and older
  • The indication of Prevnar 20® for the prevention of pneumonia caused by S. pneumoniae serotypes 8, 10A, 11A, 12F, 15B, 22F, and 33F in individuals 18 years of age and older is approved under accelerated approval based on immune responses as measured by opsonophagocytic activity (OPA) assay. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial
  • Prevnar 13® is indicated for active immunization for the prevention of pneumonia and invasive disease caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F in adults 18 years of age and older
Prevnar 13® Limitations of Use: Prevnar 13® will only help protect against S. pneumoniae serotypes in the vaccine

SELECT SAFETY INFORMATION
 
  • Do not administer Prevnar 20® or Prevnar 13® to individuals with severe allergic reaction (eg, anaphylaxis) to any component of Prevnar 20® or Prevnar 13® or to diphtheria toxoid
  • Safety and immunogenicity data on Prevnar 20® are not available for individuals in immunocompromised groups and vaccination should be considered on an individual basis. Based on experience with pneumococcal vaccines, individuals with altered immunocompetence may have reduced immune responses to Prevnar 20®
IMPORTANT SAFETY INFORMATION
  • Do not administer Prevnar 20® or Prevnar 13® to individuals with severe allergic reaction (eg, anaphylaxis) to any component of Prevnar 20® or Prevnar 13® or to diphtheria toxoid
  • Safety and immunogenicity data on Prevnar 20® are not available for individuals in immunocompromised groups and vaccination should be considered on an individual basis. Based on experience with pneumococcal vaccines, individuals with altered immunocompetence may have reduced immune responses to Prevnar 20®
  • Immunocompromised individuals or individuals with impaired immune responsiveness due to the use of immunosuppressive therapy may have reduced antibody response to Prevnar 13®
  • For Prevnar 20® in individuals 18 years of age and older, the most commonly reported solicited adverse reactions (>10%) were pain at the injection site, muscle pain, fatigue, headache, and arthralgia. Additionally, injection site swelling was also reported (>10%) in individuals 18 through 59 years of age
  • For Prevnar 13®, in adults 18 years of age and older, the most commonly reported solicited adverse reactions (>5%) were pain, redness, and swelling at the injection site, limitation of arm movement, fatigue, headache, muscle pain, joint pain, decreased appetite, vomiting, fever, chills, and rash
Patients should always ask their healthcare providers for medical advice about adverse events. You are encouraged to report negative side effects of vaccines to the US Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC). Visit http://www.vaers.hhs.gov or call 1-800-822-7967.

Please click for Prevnar 20® Full Prescribing Information.

Please click for Prevnar 13® Full Prescribing Information.INDICATIONS
  • Prevnar 20® is indicated for active immunization for the prevention of invasive disease caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F in individuals 6 weeks of age and older
  • Prevnar 20® is indicated for active immunization for the prevention of pneumonia caused by S. pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F in individuals 18 years of age and older
  • The indication of Prevnar 20® for the prevention of pneumonia caused by S. pneumoniae serotypes 8, 10A, 11A, 12F, 15B, 22F, and 33F in individuals 18 years of age and older is approved under accelerated approval based on immune responses as measured by opsonophagocytic activity (OPA) assay. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial
  • Prevnar 13® is indicated for active immunization for the prevention of pneumonia and invasive disease caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F in adults 18 years of age and older
Prevnar 13® Limitations of Use: Prevnar 13® will only help protect against S. pneumoniae serotypes in the vaccine